The largest decline was in children under two years of age. In this group, the rate of disease was 69 percent lower in 2001 than the base-line rate (59.0 cases per 100,000 vs. 188.0 per 100,000, P<0.001)
Pneumoccal vaccine works. But invasive disease remains relatively rare. When parents ask me if I think it's essential, I can't say yes.