CDC - Dead Bugs Don't Mutate: Susceptibility Issues in the Emergence of Bacterial Resistance

In this interesting, but somewhat heavy paper, Dr Stratton discusses the problems with antibiotic resistance, and introduces the reader to a new calss of antibiotics - the ketolides.  There's also a nice review on medscape (ugh .. login required) that reviews telithromycin.  Unfortunately, the review misses the important differentiator for telithromycin: it is bacteriocidal at standard dosages .. while zithro and claritho are more likely to be bacteriostatic.  This is important, since, as Dr Stratton points out - dead bugs don't mutate.